12-Dec-14 9:45 AM  CST

No Proof Statins Reduce Risk of Fracture Study Says

Previous reports concerning cholesterol-lowering drugs known as statins indicated that patients who took statins had a decreased risk for fractures. However a study released this week states the reports are unsubstantiated. The study, which involved 18,000 older adults, involved the drug Crestor (rosuvastatin) and an inactive placebo. During the study a total of 431 patients suffered a bone fracture. 221 of those patients that were diagnosed with a bone fracture were taking Crestor (rosuvastatin) and 210 were taking the placebo.

Researchers state that even though this particular study only involved the drug Crestor, other studies involving other commonly prescribed statins have had similar results. The results of the study, which were published in the Journal of American Medical Association (JAMA) involve men older than 50 and women older than 60. Those patients that were part of the study were followed for a period of 5 years, with a follow up time that averaged every two years. Both groups, those taking Crestor and those taking the placebo were found to have similar issues and were observed for following issues, smoking rates, blood pressure, alcohol intakes, weight control, and exercise levels.

Other studies in the past have hinted that there is a connection between heart health and osteoporosis, a condition marked by thinning bone and an increased risk for fracture. It was thought that there may have been a link between inflammation and atherosclerosis, hardening of the artery walls, but the link seems to have been disproven. Researchers can find no positive connection between the C-reactive protein, a protein known to be associated with inflammation, and bone fractures. Because researches have been unable to find an undeniable link between heart disease and osteoporosis, the common thought that statins help protect from patients from an increased risk for bone fracture seems to be false.





Reinberg, S., (2014) “Statins won’t help protect bones from fracture, studies say”, HealthDay, http://consumer.healthday.com/bone-and-joint-information-4/bone-joint-and-tendon-news-72/statins-won-t-help-protect-bones-study-694219.html, retrieved 5. December 2014

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Source: Sandy Andrews  

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